Characteristics | Details |
---|---|
Active Ingredients | Avanafil 100 mg, Dapoxetine 60 mg |
Form | Oral Tablets |
Manufacturer | Sunrise Remedies Pvt. Ltd. |
Duration of Effect | Up to 6 hours |
Discover More About Top Avana |
Pharmacokinetics
Top Avana combines Avanafil and Dapoxetine. Avanafil, a phosphodiesterase type 5 inhibitor, enhances erectile function. After oral administration, Avanafil rapidly absorbs into the bloodstream, reaching peak plasma concentrations within 30 to 45 minutes. Its bioavailability supports a swift onset of action. Dapoxetine, a selective serotonin reuptake inhibitor, mitigates premature ejaculation. It also achieves peak plasma levels swiftly, within approximately one to two hours.
Both active ingredients metabolize extensively in the liver, primarily via cytochrome P450 enzymes. Their half-lives differ; Avanafil at 5 to 7 hours, and Dapoxetine at around 19 hours. Elimination occurs predominantly through renal and fecal excretion. Pharmacokinetic profiles do not significantly alter with food intake, though high-fat meals might delay absorption. The combination achieves therapeutic outcomes while maintaining a favorable safety profile.
Correct Use
Optimal efficacy of Top Avana depends on proper usage. Ingest a single tablet with water 30 minutes prior to sexual activity. Avoid consuming more than one dose within a 24-hour period. Alcohol and grapefruit juice may exacerbate side effects, thus warrant caution.
Assess individual tolerance. Start with the lowest effective dose. Patients with hepatic or renal impairment should consult healthcare providers before initiating treatment. Consider patient-specific factors such as concomitant medications or existing medical conditions.
Top Avana Precautions
Exercise caution in patients with cardiovascular disorders. Top Avana’s vasodilatory effects may impact blood pressure. Individuals with a history of stroke, heart attack, or severe arrhythmias should seek medical advice. Top Avana is not intended for use in women or individuals under 18 years.
Monitor for signs of hypersensitivity or allergic reactions. Discontinue use if symptoms such as rash, swelling, or difficulty breathing occur. Consult with healthcare providers to ascertain the suitability of Top Avana for those with anatomical penile deformation.
Pregnancy and Breastfeeding
Top Avana is contraindicated during pregnancy and lactation. The combination targets male sexual health, rendering its use in women unnecessary and potentially harmful. Animal studies indicate potential reproductive toxicity; human data remains unavailable. Pregnant or nursing individuals should avoid exposure.
Top Avana Side Effects
Common side effects include headaches, dizziness, and nausea. Some may experience flushing or nasal congestion. Serious adverse events are rare but possible, such as priapism or syncope. Promptly seek medical attention if these occur.
- Headache
- Dizziness
- Nausea
- Flushing
- Nasal congestion
Report any unexpected reactions to a healthcare professional. Dose adjustments may alleviate mild symptoms. Discontinue and assess for alternative therapies if severe effects persist.
Top Avana Over The Counter
Top Avana requires a prescription. The combination targets specific health issues necessitating medical oversight. Self-medication could lead to adverse interactions with existing treatments or health conditions. Ensure thorough consultation prior to use.
While not available over the counter, licensed pharmacies provide access with a valid prescription. Verify the authenticity of the source to mitigate risks of counterfeit products. Opt for pharmacies with established reputations and regulatory compliance.
Data origin:
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